Abstract：A differential pulse voltammetric method for simultaneous determination of 4-aminophen and acetaminophen with graphene modified glass carbon electrode was developed.Both of the two compounds gave well defined oxidation voltammetric peaks at modified electrode in medium of pH 5.72 Britton-Robinson buffer.As a result,it is possible to simultaneously determine these two compounds.Under the optimum conditions,the linear ranges of 4-aminophen and acetaminophen were 0.1～1.8 and 0.2～2.2 mg·mL-1,with detection limits of 0.067 and 0.074 mg·mL-1,respectively.This method was successfully applied for the determination of acetaminophen and 4-aminophen in serum to obtain satisfied results.
2012, Vol. 36 
