Abstract: Objective To investigate the value of multislice spiral computed tomography angiography(MSCTA) in the diagnosis and treatment of portal hypertension(PTH).Methods The MSCTA was performed in 50 PHT patients to observe portal vein anatomy,portal-collateral circulation,and the shape,location and blood supply of esophageal varices.Results Among the 50 PHT patients,the demonstration of portal-collateral circulation showed lower esophageal varices in 94.0%,gastrict fundus varices in 90.0%,left gastric varices in 90.0%,paraesophageal varices in 72.0%,short and posterior gastric varices in 32.0%,splenic/gastric vein to renal vein shunt in 28.0%,venae paraumbilicales and abdominal wall varices in 26.0%,and retroperitoneal-paravertebral varices in 22.0%.Twenty-one patients underwent operation,and the surgical diagnosis completely accorded with the imaging diagnosis.The symptoms of 49 GV positive patients detected by MSCTA had good consistency with those found at gastroscopy.Conclusion The MSCTA can provide a reliable basis for determining pathological severity,predicting complications and selecting treatment options in portal hypertension