Abstract： Objective The investigate the adjuvant treatment of acute left heart failure complicated by hypoxemia with noninvasive BiPAP ventilation.Methods Thirty-four patients with acute left ventricular failure treated in our hospital from June 2008 to September 2010 were randomly divided into two groups.All patients received ECG monitoring,continuous arterial blood gas analysis and the treatment with cardiotonics,diuretic,vasodilator and other conventional drugs.Control group(n=16) was given high-flow oxygen by nasal catheter(6 L·min-1) and BiPAP treatment group(n=18) was given oxygen by BiPAP breathing machine.Results Values of PaO2 and SaO2 significantly increased but heart rate and respiratory rate obviously decreased in both groups after treatment for 1 and 6 hours(P<0.01).Compared with control group,noninvasive BiPAP ventilation induced significant increase in PaO2 and SaO2 and obvious decrease in heart rate and respiratory rate(P<0.01).After treatment for 1 hour,the total effective rate in BiPAP treatment group was significantly higher than that in control group(88.9% vs 50.0%,P<0.05).Two patients in BiPAP treatment group(11.1%) and 8 patients in control group(50.0%)were converted to receive endotracheal intubation due to ineffective treatment.There was a significant difference in endotracheal intubation rate between the two groups(P<0.05).Conclusion Compared with conventional drug therapy,noninvasive BiPAP ventilation is more conducive to remission of acute left heart failure.Therefore,noninvasive BiPAP ventilation has great value for improving the survival rates in patients with heart failure.
2011, Vol. 53 
