Abstract： Objective To evaluate the value of CT perfusion imaging in chemotherapy for intermediate and advanced stage cancer of uterine cervix.Methods The 64-slice CT perfusion imaging was performed in 56 patients with cervical cancer stage Ⅱb or higher before chemotherapy.The blood flow(BF),blood volume(BV),mean transit time(MTT) and permeability of surface(PS)were recorded and tumor size was calculated in all patients.Then enhanced CT was carried out to calculate tumor size 3 weeks after two courses of chemotherapy(TP scheme).Results There were significant differences in BV and PS among patients with complete remission,patients with partial remission,patients with progressive disease and patients with stable disease(P<0.05).The BV and PS in patients who received effective chemotherapy were greater than those in other patients.There were no significant differences in BF and MTT among patients with different clinical outcomes(P>0.05).Conclusion The CT perfusion imaging can measure BV and PS before chemotherapy so as to provide a basis for the treatment of intermediate and advanced stage cancer of uterine cervix.
2011, Vol. 53 
