XU Li,YANG Ying-zhou,TAN Wei-guo,WU Qing-fang,ZHANG Yu-hua,LUO Yu-xi (Department of Tuberculosis Control,Institution for Prevention and Treatment of Chronic Disease in Shenzhen,Shenzhen 258020,China)
摘要目的研究FIP200(FAK-family interacting protein of 200 kDa)对细胞外基质成份诱导的呼吸道上皮细胞粘附和迁移的影响及其作用机制。方法通过纤连接蛋白(finbronectin,FN)诱导培养呼吸道上皮细胞的粘附迁移,以FIP200反义寡核苷酸(ODN)经脂质体转染细胞;以计数法测定细胞粘附率
Abstract:Objective To investigate the effects of FIP200 on the cell adhesion and migration of human airway epithelial cell stimulated by fibronectin.Methods The human airway epithelial cells were cultured and stimulated by fibronectin.FIP200 antisense oligodeoxynu