Application of Enteral Nutrition in Patients with Chronic Obstructive Pulmonary Disease Accompanied by Respiratory Failure Receiving Non-invasive Positive Pressure Ventilation
ZHANG Yun-jiao,WAN Yu,AI Hua,YANG Dan-rong,SHEN Ce
Abstract： Objective To explore the clinical value of enteral nutrition in patients with chronic obstructive pulmonary disease(COPD) accompanied by respiratory failure who had received non-invasive positive pressure ventilation(NIPPV).Methods Fifty-two patients with COPD and respiratory failure who had received NIPPV were randomly divided into enteral nutrition group and control group,with 26 patients in each group.All patients received anti-infection and symptomatic treatment.In addition,patients in enteral nutrition group were given intestinal nutrition via indwelling nasogastric tubes for 15 days.The concentrations of hemoglobin,plasma total protein and albumin,body weight,triceps skin fold thickness,upper arm muscle circumference,the duration of NIPPV,the number of patients receiving invasive mechanical ventilation and the length of ICU stay were measured before and after treatment.Results Compared with pretreatment values,blood biochemical parameters and body mass index values significantly increased 15 days after treatment in enteral nutrition group(P<0.05).Compared with control group,enteral nutrition obviously increased blood biochemical parameters and body mass index values,and decreased the duration of NIPPV,the length of ICU stay and the rate of invasive mechanical ventilation usage(P<0.05).Conclusion Enteral nutrition can improve nutritional status,shorten the duration of NIPPV and the length of ICU stay,and decrease the rate of invasive mechanical ventilation usage in patients with COPD accompanied by respiratory failure.
2011, Vol. 53 
