ZHOU Yanga,LIU Zhi-lib,SHU Yongb,LUO Yunb,HUANG Weia,XIE Zhi-boa(a.2007 Grade of Medical Department of Graduate School;b.Department ofOrthopaedics,the First Affiliated Hospital,Nanchang University,Nanchang 330006,China)
摘要目的研究浅蓝菌素(cerulenin)对人成骨肉瘤细胞U2-OS在裸鼠体内生长抑制作用。方法建立人成骨肉瘤细胞U2-OS BALB/C裸鼠瘤模型。18只成瘤裸鼠按随机数字表分成3组,每组6只;对照组(DMSO溶剂)、低剂量cerulenin组(0.2 mL cerulenin配制液40 mg.kg-1.次-1)、高剂量cerulenin组(0.2
Abstract：Objective To investigate the inhibitory effect of fatty acid synthase inhibitor,cerulenin,on the growth of transplanted tumors of human osteosarcoma(U2-OS) in nude mice.Methods U2-OS human osteosarcoma xenografts were used as preclinical tumor models.The
2010, Vol. 52 