Abstract：Objective To observe the clinical effect of lornoxicam combined with tamsulosin on acute renal colic.Methods Forty-six patients with acute renal colic were divided into two groups,with 23 patients in each group.The observation group was given intramuscular injection of 8 mg lornoxicam and oral administration of 0.2 mg tamsulosin.The control group was given intramuscular injection of 50 mg pethidine hydrochloride and 10 mg anisodamine.Analgesic effect,adverse events and pain recurrence were recorded in both groups.Results There were no significant differences in analgesic effect and incidence of gastrointestinal symptoms between the two groups(P=0.35,P=0.208).Compared with control group,the incidences of neuropsychiatric events and other adverse reactions obviously decreased in observation group(P<0.05).Recurrence rate of renal colic was 60.9%(14 patients) in observation group and 91.3%(21 patients) in control group,and the difference was significant between the two groups(P=0.035).Conclusion The lornoxicam combined with tamsulosin was effective in the treatment of renal colic,with few adverse effects,low recurrence rate,safe re-use and non-addictive habit formation.
2012, Vol. 5 
