Abstract:Objective To compare the accuracy of 64-slice CT and intravascular ultrasound(IVUS)for the evaluation of coronary atherosclerotic plaque characteristics.Methods A retrospective analysis was performed in 29 coronary heart disease patients who were treated in our hospital between January 2009 and October 2010.All patients underwent both 64-slice CT and IVUS.According to ultrasound-defined plaque composition,plaques were classified as fibrous,lipid-rich,and calcified plaques.Plaque burden,plaque area and lumen area were detected by 64-slice CT and IVUS,respectively.The CT value was compared among the three types of plaques.Results There were no significant differences in plaque burden,plaque area and lumen area between 64 slice CT and IVUS [(57.54±13.32) %,(8.59±2.38) mm 2 and(6.26±2.53) mm 2 vs(57.52± 13.47) %,(8.43±2.52) mm 2 and(6.68±2.34) mm 2,respectively;P>0.05 ].Compared with calcified plaques,CT values of fibrous plaques and lipid-rich plaques significantly decreased [(57.46±6.78) Hu and(59.32±6.64) Hu vs(726.36±56.78) Hu,respectively;P<0.05 ].Conclusion The 64-slice CT possesses a certain accuracy for the detection of coronary artery plaques,especially for distinguishing calcified plaques.Therefore,it can be used as the first choice for the detection of coronary artery plaques.