Abstract:Objective To investigate the feasibility and safety of nasopharyngeal airway combined with face mask ventilation in surgical removal of breast lumps.Methods Sixty patients undergoing surgical removal of breast lumps were randomly assigned to receive either nasopharyngeal airway combined with face mask ventilation(group A,n=30) or laryngeal mask airway(group B,n=30).Mean arterial pressure(MAP),heart rate(HR),end-tidal carbon dioxide concentration(PETCO2) and inhaled concentration of sevoflurane were determined before induction(T0),at 0,5 and 10 minutes after the insertion of nasopharyngeal airway or laryngeal mask airway(T1,T2 and T3),at 5 and 10 minutes after the start of surgery(T4,T5),and at the end of ventilation(T6).In addition,wake-up time(the period from stopping sevoflurane inhalation to eye opening),the time of ventilation mask removal(the period from stopping sevoflurane inhalation to wake-up) and adverse reactions(upper airway obstruction during surgery,regurgitation and aspiration during anesthesia,body movement and postoperative throat discomfort) were recorded in both groups.Results All patients could keep spontaneous breathing well after induction.The PETCO2 at T0 was significantly lower than that at T1 or T2(P<0.05).Compared with group A,the MAP and HR measured at T1 and T6 and inhaled concentrations of sevoflurane measured at T2 and T3 obviously increased in group B(P<0.05).There were no significant differences in wake-up time and time of ventilation mask removal between the two groups(P>0.05).Moreover,the incidence of postoperative throat discomfort in group B was obviously higher than that in group A(P<0.05).Conclusion Nasopharyngeal airway combined with mask ventilation is effective and safe in surgical removal of breast lumps.