Abstract：Objective To observe the effects of dexmedetomidine on arousal quality,hemodynamics and postoperative shivering in patients undergoing scoliosis surgery.Methods Forty patients scheduled for posterior scoliosis correction(ASA Ⅰ-Ⅱ,aged 10-25 years) were randomly divided into two groups,with 20 patients in each group.Group D was given intravenous injection of dexmedetomidine(0.5 μg·kg-1) within 10 minutes before induction,followed by an intraoperative infusion of dexmedetomidine(0.5 μg·kg-1·h-1) until the incision was sutured.Group C was only infused with an equal volume of normal saline.All infusions were discontinued at 15 minutes before awaken test,and restored after the test.Surgery duration,wake-up time,awakening time from anesthesia,intraoperative mean arterial pressure(MAP) and heart rate(HR) were recorded.Moreover,arousal quality,use of vasoactive drugs and postoperative shivering were determined.Results There were no significant differences in arousal time and awakening time from anesthesia between the two groups(P>0.05).Compared with group C,intraoperative infusion of dexmedetomidine significantly increased arousal quality and decreased MAP,HR and postoperative shivering rate(P<0.05).Conclusion Continuous infusion of small doses of dexmedetomidine can improve arousal quality,maintain hemodynamic stability and reduce the incidence of postoperative shivering in scoliosis surgery.
2012, Vol. 52 
