Abstract：Objective To investigate the clinical significance of thrombin-activatable fibrinolysis inhibitor(TAFI) detection in patients with pulmonary embolism.Methods Plasma TAFI Ag levels and TAFI activity(TAFI-a)were determined in 125 patients with massive pulmonary embolism(group A1),131 patients with submassive pulmonary embolism(group A2),124 patients with low risk embolism(group A3) and 140 heathy controls.Results Compared with heathy controls,TAFI Ag levels and TAFI-a significantly increased in patients with pulmonary embolism(P<0.001).Moreover,there were significant differences among group A1,group A2 and group A3(P<0.05).Conclusion Plasma TAFI detection is valuable in the diagnosis and treatment of pulmonary embolism.
2012, Vol. 5 
