Abstract:Objective To study the relationship between XbaⅠand PvuⅡpolymorphisms of estrogen receptor α(ERα) gene and bone mineral density(BMD) in postmenopausal women in Nanchang.Methods The BMD was measured by dual energy X-ray absorptiometry and PvuⅡ and XbaⅠ polymorphisms were detected by PCR-RFLP in 160 postmenopausal women.Results There were no relationship between XX,Xx and xx genotypes of XbaⅠpolymorphism or PP,Pp and pp genotypes of PvuⅡ polymorphism and BMD of lumbar spine(L1-L4),femoral neck,greater trochanter and Ward’s triangle(P>0.05).Conclusion There were no relationship between polymorhisms of XbaⅠand PvuⅡgenotypes and BMD in postmenopausal women in Nanchang.
熊林; 彭维杰; 钟敬亮; 杨琳; 刘永飞. 雌激素受体α基因XbaⅠ、PvuⅡ位点基因多态性与南昌地区绝经后妇女骨密度的关系[J]. 南昌大学学报(医学版), 2012, 52(05): 5-.
XIONG Lin1,PENG Wei-jie2,ZHONG Jing-liang2,YANG Lin2,LIU Yong-fei3. Relationship between XbaⅠand PvuⅡ Polymorphisms of Estrogen Receptor α Gene and Bone Mineral Density in Postmenopausal Women in Nanchang. , 2012, 52(05): 5-.