Abstract：Objective To explore the prevention,treatment,timing of pregnancy termination,and delivery methods in patients with eclampsia,and to improve the prevention and treatment of eclampsia and reduce maternal and perinatal mortality.Methods Thirty-seven patients with eclampsia were treated with magnesium sulfate,mannitol,diazepam and morphine or lytic cocktail.Patients with unsatisfactory blood pressure control were given additional phentolamine or labetalol pyridine.The effects of timing of pregnancy termination and delivery methods on mothers and children were investigated in patients with eclampsia.Results The proportion of babies with Apgar score 0-3 at 1 minute in patients undergoing pregnancy termination <2 and ≥6 hours was significantly higher than that in patients undergoing pregnancy termination ≥2-<6 hours(all P<0.05).The proportion of babies with Apgar score 4-7 at 1 minute in patients undergoing pregnancy termination <2 hours was significantly higher than that in patients undergoing pregnancy termination ≥2-<6 and ≥6 hours(all P<0.05).The proportion of babies with Apgar score 8-10 at 1 minute in patients undergoing pregnancy termination <2 and ≥6 hours was significantly lower than that in patients undergoing pregnancy termination ≥2-<6 hours(all P<0.05).There were no obvious differences in perinatal mortality among patients undergoing pregnancy termination <2,≥2-<6 and ≥6 hours(P>0.05).The proportion of babies with Apgar score 0-3 at 1 minute born by vaginal delivery was significantly higher than that of babies born by cesarean section(P<0.05).The proportion of babies with Apgar score 4-7 at 1 minute born by vaginal delivery was not different from that of babies born by cesarean section(P>0.05).The proportion of babies with Apgar score 8-10 at 1 minute born by vaginal delivery was significantly lower than that of babies born by cesarean section(P<0.05).Among the 37 patients,prenatal examination was performed in 7 and complications occurred 25 times.Conclusion Pregnancy termination performed at 2-6 hours after seizure control by cesarean section in antenatal and intrapartum eclampsia can reduce the incidence of perinatal asphyxia.Moreover,careful prenatal monitoring,early detection of pregnancy-induced hypertension,positive and proper treatment,and timely pregnancy termination after seizure control can improve the prognosis in patients with eclampsia.
2012, Vol. 52 
