Abstract：Objective To investigate the clinical characteristics,diagnosis and treatment of duodenal stromal tumor.Methods Data of 15 cases of confirmed duodenal stromal tumor were retrospectively analyzed.Results The most common symptoms in patients with duodenal stromal tumor were upper gastrointestinal bleeding,abdominal pain,abdominal distension and abdominal mass.The duodenal stromal tumor was mainly located in the descending descending part and horizontal part,and was diagnosed by endoscopy,ultrasonic endoscope,upper gastrointestinal barium meal,CT or MRI,and type B ultrasonography.Immunohistochemical testing showed CD117 positive in 14 cases and CD34 positive in 10.All patients were treated with pancreaticoduodenal surgery alone or in combination with imatinib mesylate and had good prognosis.Conclusion Clinical manifestations of duodenal stromal tumor are non-specific,and reasonable endoscopic and imaging examination can improve the detection rate.Histopathological and immunohistochemical tests are important means for final diagnosis,and early surgery combined with imatinib mesylate is the main treatment at present.
2012, Vol. 52 
