Abstract：Objective To evaluate the effectiveness of lipid-lowering treatment in hyperlipidemic-severe acute pancreatitis(HL-SAP) through comparison with conventional treatment.Methods Sixty-one patients with HL-SAP were divided into two groups according to different treatment strategies.The control group(n=28) was conventionally treated with fasting,continuous gastrointestinal decompression,conventional acid suppression,anti-inflammatory,inhibition of pancreatin secretion,compound Danshen injection,rhubarb infused decocotion and expectant supportive therapy.The study group(n=33) was given low-molecular-weight heparin calcium injection and insulin injection based on conventional treatment.The time courses of decrease in triacylglycerol(TG) concentrations to 5.65 mmol·L-1,return of serum amylase and C-reactive protein(CRP) levels to normal,abdominal pain deprivation and ascites subsidence were observed in both groups.Results Time courses of decrease in triacylglycerol(TG) concentrations to 5.65 mmol·L-1,return of serum amylase levels to normal,return of C-reactive protein(CRP) levels to normal,abdominal pain deprivation and ascites subsidence were,respectively,(5.6±1.6),(3.7±1.2),(8.1±3.2),(5.8±2.2) and(11±2.8) days in control group,and(3.4±1.1),(2.1±0.9),(6.8±2.5),(4.1± 1.8) and(6.7 ±2.5) days in study group,and differences were significant between the two groups(P<0.05 or P<0.01).Conclusion The recovery of TG levels is correlated with clinical symptoms,sign remission and course decurtation in patients with HL-SAP.Low-molecular-weight heparin calcium injection and insulin injection are necessary,safe and effective in lipid-lowering therapy on HL-SAP.
引用本文:
杨宇龙； 王农荣. 高脂血症性重症急性胰腺炎降脂治疗与病情转归的关系[J]. 南昌大学学报（医学版）, 2012, 52(01): 56-58.
YANG Yu-long,WANG Nong-rong. Relationship between Lipid-lowering Therapy on Acute Severe Hyperlipidemic Pancreatitis and Disease Outcome. , 2012, 52(01): 56-58.
2012, Vol. 52 
