HUANG Hui-minga,b,LIANG Huib,LI Minb,CHEN Gen-linb,LIU Cheng-meia(a.State Key Laboratory of Food Science and Technology,Nanchang 330029,China;b.Medical Department of Graduate School,Nanchang University,Nanchang 330006,China)
Abstract:Objective To explore the synthesis of glycine derivatives as aminopeptidase N(APN) inhibitors.Methods Based on the known structure of peptide-like derivatives as APN inhibitors,three series of acetamide derivatives were designed and synthesized.Results Th