PENG Lin1,ZHANG Hao1,TANG Jing2,ZHANG Xian-ming1(1.Department of Nephrology,The Third Xiangya Hospital of Central South University,Changsha 410013,China;2.Department of Nephrology,Affiliated Nanhua Hospitalof Nanhua University,Hengyang 421002,China)
Abstract:Objective:To investigate the mechanism of renal interstitial fibrosis after unilateral ureteral obstruction and the renoprotective effect of MMF.Methods: Fifty-four rats were randomly assigned to shame operation group,operation group and MMF(15mg·kg-1·d